INFLUENCE OF RADON-PHARMACOTHERAPY COMPLEX ON THE ENERGY BALANCE OF ANIMALS WITH BRONCHO-PULMONARY PATHOLOGY

Galachenko А.А., Galachenko V.V.

Сlinical sanatorium «Avangard», Nemirov

(galachenko@mail.ru, t/f +38(04331)21713)

Recently attention the researchers is focused on study of infringements of bioenergy function of organism with different diseases of respiratory apparatus. However, opportunity of medical correction of given infringements, including on a background of application spa factors, are investigated insufficiently.

The purpose of work: research of activity key enzymes of energy exchange in conditions experimental broncho-pulmonary pathology on a background combination use of radon water and Thiotriazolin with N-acetylcystein. Is proved, that on 1 and 5 day of development of the broncho-pulmonary pathology in control group the levels of adenosine triphosphate (ATP) and adenosine diphosphate (ADP) are reduced (р<0,05) on 29% and 19%, accordingly, in comparison with intact animals. Uses of radon water with pharmacotherapy prevent decrease of the contents АТP on 30-34%, АDP — on 18-20% in relation to characteristics of animals of control group. The complex of radonof water with a researched combination of preparations authentically raises a level adenosine monophosphate (АМP) compared with a control series. Increase of quantity of all adenylic nucleotides on a background of application of radon water with pharmacological correction indicate on properties of a researched complex to normalize, and it is possible, and to stimulate processes oxidizing phosphorylation in organism of animals with broncho-pulmonary pathology, and also to prophylaxes destruction of high-energy bonds.

Thus, the results of this researches convincingly demonstrate, that complex use of radon water in a combination with Thiotriazolin and N-acetylcystein have expressed therapeutic effect on current of a pathology of the broncho-pulmonary system at rats, that is displayed in significant intensification at them processes synthesis of energy.

Комплексное использование радоновой воды в комбинации с тиотриазолином и N-ацетилцистеином оказывет выраженный терапевтический эффект на течение патологии бронхо-легочной системы у крыс, что проявляется в значительной интенсификации у них энергосинтезирующих процессов.